Flavay® scores the highest both as an antioxidant
and as a free radical scavenger.

Special Report:
Independent Comparative Analysis

Independent Comparative Analysis of Flavay® With Grape Seed Extract and French Pine Bark Extract

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More than 60 years of solid scientific research, patents and clinical studies, rigorous manufacturing controls and comprehensive identity testing to safeguard quality and consistency, Flavay® is produced at the same French manufacturing facilities for pharmaceutical over-the-counter and dietary supplement uses worldwide. Flavay® is the name you can trust for pure and unadulterated authentic small-cluster OPCs manufactured in France for over 60 years.

Dr. Masquelier's 1948 French Patent described a method to extract the active principles in Flavay® from the bark of the pinus Maritima (French Maritime pine). His 1970 French Patent described an even more efficient extraction method of the active principles from the seeds of the vitis vinifera grapes. In 1987 Dr. Masquelier was awarded a now-expired U.S. patent to describe proanthocyanidins for use as a powerful antioxidant, "which has a radical scavenger effect."

The marketplace is full of many imitation extracts and blends.

Now the marketplace is full of imitations, various “extracts” and derivative forms and blends of Dr. Masquelier’s scientifically proven complexes. Unfortunately, many have used Dr. Masquelier’s name and research in unauthorized ways to promote a myriad of derivations. In fact, the other "leading brand" French pine bark extract, compared to Flavay® below, is an offshoot derived from Dr. Masquelier's authentic work and products. But, independent comparative testing demonstrates that the initial qualifying research conducted on the authentic products may not be automatically transferred to other commercial products.

Flavay® is the authentic small-cluster proanthocyanidins complex derived from French pine bark and grape seeds—pure and unadulteratedused in the actual experiments by which Dr. Jack Masquelier established the "Radical Scavenger Effect."(1-3)

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As demonstrated below, Flavay® remains unsurpassed when compared to other leading brands.

Independent Lab Report Results and Conclusions

A highly qualified independent U.S. Laboratory performed five analytical methods to put in qualitative perspective the differences between Flavay® (extracted from both vitis vinifera grape seeds and French Maritime pine bark) and ten grape seed extracts currently on the market. Later, a new study was performed to include the leading French pine bark extract (sample #14). Below are the results of these studies.

Electrochemical Antioxidant Activity (ECA) Test

The below ECA chromatograms represent a comparison of French pine bark extract in Flavay® vs. the other leading brand French pine bark extract. Test conditions and amounts of samples were identical. Results are displayed on the same scale. Both samples exhibit comparable positions in the peaks, confirming that both samples originate from similar source plant materials.

Flavay French pine bark extract

However, note below, the other leading brand French pine bark extract has significantly lower amounts of antioxidant compounds per unit weight. The rest of the sample is likely to be non-antioxidant inert material.

the other leading French pine bark extract

These tests prove Flavay® is unsurpassed as a free radical scavenger.

The similar fingerprints indicate the samples origiante from a similar source plant materials, but use different extraction protocols. Flavay® scores the highest—demonstrating its superior free radical scavenging effect.

Scientific Yardsticks:

Antioxidant Capacity (ACAP) Test

The below ACAP-Trolox test was performed in addition to the ECA test to establish a more balanced and certain assessment. For the most reliable impression of the antioxidant capacity of the products, two reproducible and controllable tests were used to evaluate the antioxidant character of the samples. The fluorescein-derivative antioxidant comparison with Trolox shows that the tested leading French pine bark extract (sample #14) has little more than half the antioxidant capacity (55 percent) of the French pine bark extract in Flavay® (sample #6).

Relative values of 10 grape seed extracts compared with Flavay® and another leading French pine bark extract.

Highest Values Reached = 100% (1)

#

Product

(ACAP)
Antioxidant Capacity Trolox Equivalent

(ECA)
Electrochemical Antioxidant Activity Antioxidant "Versatility"

1 grape seed extract 3% 22%
2 grape seed extract 66% 2%
3 grape seed extract 55% 22%
4 grape seed extract 34% 41%
5 Flavay®
(grape seed)
100% 89%
6 Flavay®
(French pine bark)
100% 76%
7 Flavay®
(grape seed)
93% 100%
8 grape seed extract 24% 15%
9 grape seed extract 21% 2%
10 grape seed extract 76% 74%
11 grape seed extract 14% 6%
12 grape seed extract 76% 33%
13 grape seed extract 69% 5%
14 other leading French pine bark extract 55% 23%

The other leading French pine bark extract (sample #14) is
only 30% as active as Flavay®'s French pine bark and
only 23-26% as active as Flavay®'s grape seed.

ElectroChemical Activity (ECA)

ElectroChemical Activity (ECA) represents the versatility and capacity of a substance to "communicate" with another molecule by means of exchanging electrons. Antioxidant Capacity (ACAP) is measured by testing the material's capacity to neutralize the peroxyl radical. The measurement is expressed in equivalents of a substance called "Trolox," a soluble analogue of vitamin E.

It's important to point out that sample #13 is aggressively marketed as a branded "OPC" material. However, by means of the Thin Layer Chromatography (TLC) tests, no OPCs could be detected in the product. Furthermore, sample #13 scores very low in antioxidant activity.

The other leading French pine bark extract (sample #14) is only 30 percent as electrochemically active (ECA) as Flavay®'s French pine bark. Sample #14 is only 23-26 percent as electrochemically active as Flavay®'s grape seed. The ACAP-Trolox test indicates that sample #14 has only 55 percent of the antioxidant capacity of Flavay®'s French pine bark.

Quality and Purity Test

When dissolved in water or other specific test-liquids, the limpidity (clearness, transparency) of the solutions provides a simple and good, easy to check indicator of quality and purity. Insolubles are an indicator of low quality and/or production problems.

Percentages of Insolubles: Low quality "OPC" products only partially dissolve, indicating lack of quality and purity.

Quantity of sample other brand French pine bark extract (sample #14) Flavay®'s French pine bark (sample #6)
2% in methanol 0% 0%
1% in propanol-2 32.6% 0%
1% in ethanol 2.7% 0%

Flavay® remains perfectly soluble and limpid (clear), however the other leading brand French pine bark extract fails to measure up.

Flavay® contains no insolubles. Each batch of Flavay® materials, from French Maritime (pinus Maritima) pine bark and vitis vinifera grape seeds, is tested by mixing a sample with methanol, propanol-2 and ethanol, to check for insolubles in as broad range as possible. As shown in the chart above, the other brand French pine bark extract (sample #14) shows high amounts of insolubles. Probably due to it's different extraction process, the other brand French pine bark extract fails to measure up to the quality and purity of Flavay®, which remains perfectly soluble and limpid (clear).

All of this confirms the other leading French pine bark extract is in the mediocre grape seed extract category—both for poor antioxidant performance and lack of purity.

Authentic vs. "Borrowed" Science

Consumers need to know that the marketplace is full of imitations, offshoots and derivatives of scientifically proven natural products. Those who are looking for a product that will produce the proven results and not just the "claimed" or "implied" results, want the authentic product that was used in the actual scientific research. This is especially important when you buy a product in the "grape seed extract" and "pine bark extract" product category. It is practically impossible for retailers and consumers to distinguish inferior products from quality ones. As shown above, an independent test found that no active OPCs could be detected in one leading American brand of grape seed extract even though it's labeled and aggressively marketed as a branded OPC product. All of this proves that consumers cannot be assured of the quality, bioavailability and safety of the product.

What makes Flavay® superior to other extracts?

Flavay® is the authentic small-cluster proanthocyanidins complex derived from French pine bark and grape seeds—pure and unadulteratedused in the actual experiments by which Dr. Jack Masquelier established the "Radical Scavenger Effect."(1-3)

Buy Flavay Now

More than 60 years of solid scientific research, patents and clinical studies, rigorous manufacturing controls and comprehensive identity testing to safeguard quality and consistency; produced at the same French manufacturing facilities for pharmaceutical over-the-counter and dietary supplement uses worldwide. Flavay® is the name you can trust for pure, unadulterated and authentic small-cluster OPCs manufactured in France for over 60 years.

Flavay® customers say it best:

“Flavay® is terrific. I've had concentration problems, well, for 60 years, all my life. I couldn't have direct eye contact with people when talking with them because I couldn't concentrate. I told jokes but couldn't make people laugh because I couldn't keep my concentration. Now I can look people in the eye. Now I can make people laugh! I don't know how it works but it works and it is terrific.”
Mr. Wayne S.

Flavay and Flavay Plus

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“I just wanted to write and say WOW... I was so skeptical of your product at first and really had a negative attitude when I started taking it. I am a 40yr old female with anxiety, mild ADHD and a host of Arthrtis and inflammation issues. It was a struggle for me to get out of bed everyday and focus on what needed to be done. I had no focus, no attention span, no energy, and no desire to do anything. About a week into taking Flavay, I started noticing that I could think a little clearer. My rheumatoid arthritis flare-ups weren't so bad, though I still have them. Also, I haven't been procrastinating as much and also, my boss has noticed I've been a little more social. I attribute all of this to feeling better, and having more energy. I never thought I would feel like my old self again. I don't know exactly how you do it,...but this stuff works! I am telling all of my friends to try it because you've given me my old life back! Thank you!”
Ms. L. A.

“I want to thank your company for Flavay Plus®. My aunt and grandmother had Alzheimer's. In my early 50's I was beginning to experience some memory problems, but not anymore, and I'm grateful.”
Ms. Lynne M.

NOTE: We do not compensate for our endorsements and testimonials. We do not consider paid testimonials to be nearly as valuable as comments from customers who were not compensated and yet liked the products so much they gave their testimonials anyway.
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  • SOURCES:
  • 1. Masquelier, J. Plant extract with a proanthocyanidins content as a therapeutic agent having radical scavenging effect and use thereof. U.S. Patent No. 4,698,360, 1987.
  • 2. Masquelier, J. A lifetime devoted to OPC and [pyc]. Alfa Omega Editrice, Pub., 1996.
  • 3. Schwitters, B., Masquelier, J. OPC in practice. Alfa Omega Editrice, Publishers, 1995.
  • 4. Schwitters, B., Dr. Masquelier's mark on health. Alfa Omega Editrice, Publishers, 2004.
  • 96. The International Nutrition Company Special Report, "Pine vs. Pine Comparative Analysis between Masquelier's Original Pine Bark OPCs and another leading brand pine bark extract," Oc. 1998. PhytoChem Technologies, Inc., Chelmsford, Massachusetts, Ju. 1998. The International Nutrition Company Special Report," Masquelier's Original OPCs and ten grape seed extracts; an independent, reproducible state-of-the-art comparative analysis," No. 1997.
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